ISOrTT Frequently Asked Questions (FAQ)

What is tolerance?

Tolerance after solid organ transplant is defined as the absence of anti-donor immuno-reactivity without the need for immunosuppression. Operational tolerance refers to the clinical state of being off all immunosuppression after solid organ transplant with maintained normal transplant organ function. This state has been difficult to achieve clinically in a predictable and stable fashion.

Why does ISOrTT exist?

The goal of ISOrTT is to prospectively document the outcomes of patients from multiple centers across the world that have successfully been maintained off immunosuppressive drugs after organ transplantation.

How do I get involved?

See our contact page for email access to our coordinating center staff.